Carbonate Ion → 4-[2-(3-Fluoro-pyridin-2-yl)-imidazol-1-ylmethyl]-5-propyl-6-pyridin-3-yl-pyrimidine
Reaction equation
[C:33](=[O:34])([O-:35])[O-:36].[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]([CH2:11][n:12]2[c:13](-[c:17]3[n:18][cH:19][cH:20][cH:21][c:22]3[F:23])[n:14][cH:15][cH:16]2)[c:7]1[CH2:8][CH2:9][CH3:10].[Cs+:37].[Cs+:38].[O:39]1[CH2:40][CH2:41][O:42][CH2:43][CH2:44]1.[O:47]=[C:48]([CH:49]=[CH:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1)[CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1.[O:65]=[C:66]([CH:67]=[CH:68][c:69]1[cH:70][cH:71][cH:72][cH:73][cH:74]1)[CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1.[O:83]=[C:84]([CH:85]=[CH:86][c:87]1[cH:88][cH:89][cH:90][cH:91][cH:92]1)[CH:93]=[CH:94][c:95]1[cH:96][cH:97][cH:98][cH:99][cH:100]1.[Pd:45].[Pd:46].[n:24]1[cH:25][c:26]([B:30]([OH:31])[OH:32])[cH:27][cH:28][cH:29]1>>[c:2]1(-[c:26]2[cH:25][n:24][cH:29][cH:28][cH:27]2)[n:3][cH:4][n:5][c:6]([CH2:11][n:12]2[c:13](-[c:17]3[n:18][cH:19][cH:20][cH:21][c:22]3[F:23])[n:14][cH:15][cH:16]2)[c:7]1[CH2:8][CH2:9][CH3:10]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-10990059479245b3ba095eff402e6c78
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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