Toluene → HCID 71073579, compound

Participants

Reaction Steps

First, 5 g of ethyl 2-naphthalenecarboximidate hydrochloride, 50 mL of toluene, and 4.3 g of triethylamine (Et3N) were put into a 300-mL three-neck flask and the mixture was stirred at room temperature for 10 minutes. With a 50-mL dropping funnel, a mixed solution of 2.3 g of butyryl chloride and 30 mL of toluene was added dropwise to this mixture, and the mixture was stirred at room temperature for 41.5 hours. After a predetermined time elapsed, the reaction mixture was suction-filtered, and the filtrate was concentrated to give N-(1-ethoxy-2-naphthylidene)butyramide (a yellow oily substance, 100% yield). The synthesis scheme of Step 1 is shown in (F-1) below.

Provenance & Evidence