P-Toluenesulfonylhydrazide → HCID 89760726, compound

Participants

Reaction Steps

4-Fluoro-benzaldehyde (26.6 ml, 31.25 g, 251 mmol) was added all at once to a stirred suspension of 4-tolylsulfonyl hydrazine (43.47 g, 287 mmol) in methanol (200 ml). Within 30 seconds everything dissolved and there was a small exotherm to 32° C., before the temperature dropped. After 30 minutes some of the solvent was evaporated. Crystallisation started after scratching and the solution was left for two hours at room temperature and overnight at ca 5° C. to crystallize. The crystals were filtered off, washed with methanol (2×ca 30 ml), then left in the air to dry, yielding 51.8 g (71%) m.p. 123-125° C.

Provenance & Evidence