Trifluoroacetate → Hexafluoroacetylacetone

HRID 1479682Notes

Reaction equation

HRID 1479682 reaction equation
[F:1][C:2]([F:7])([F:6])[C:3]([O-:5])=O.[F:8][C:9]([F:19])([F:18])[C:10](=[O:17])[C:11]#CC(F)(F)F>O>[CH2:11]([C:3]([C:2]([F:7])([F:6])[F:1])=[O:5])[C:10]([C:9]([F:19])([F:18])[F:8])=[O:17]

Participants

4

Reactant 2

HCID 84468TrifluoroacetateHCID 133338661,1,1,5,5,5-Hexafluoropent-3-yn-2-one

Product 1

HCID 73706Hexafluoroacetylacetone

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In view of the above circumstances, the present inventors have made extensive researches and resultantly found that: it is possible to form a 1,1,1,5,5,5-hexafluoroacetylacetone hydrate by reacting a 3,3,3-trifluoropropynyl metal with a trifluoroacetate and then bringing the resulting reaction mixture (A), in which at least 1,1,1,5,5,5-hexafluoro-3-pentyn-2-one or an equivalent thereof is contained, into contact with water in the presence of an acid; and it is possible to produce 1,1,1,5,5,5-hexafluoroacetylacetone by dehydration of the thus-formed hydrate.

Sources & evidence

ORD record
ord-dba1c7226ec54fc0a39bcab722641521
Source dataset
uspto-grants-2016_08
Patent number
US09409843B2

Reaction notes

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