1,2-Dichloroethane → 1,2-Dimethyl-3-nitrobenzene

Participants

Reaction Conditions

Reaction Steps

A 250 mL three-necked round bottom flask fitted with reverse dean-stark apparatus was charged with 10.62 g o-xylene (0.1 mol), 60 mL 1,2 dichloro ethane, and 2.12 g of catalyst as prepared in example 5. The reaction flask was flushed with nitrogen. The reaction mixture was refluxed at 110° C. for 1 h followed by the dropwise addition of 11.35 mL (0.2 mol) 70% HNO3. The water formed during the reaction was removed using the reverse dean-stark apparatus. The reaction was carried out for 16 h. The reaction was monitored by GC analysis. In this reaction 94.9% conversion of o-xylene was obtained with 48.0% and 51.1% 3-nitro o-xylene (3NOx) and 4-nitro o-xylene (4NOx), respectively. Other unidentified products were 0.9%.

Provenance & Evidence