1,2-Dichloroethane → 1,2-Dimethyl-3-nitrobenzene

Participants

Reaction Conditions

Reaction Steps

The 250 mL three-necked round bottom flask fitted with reverse dean-stark apparatus was charged with 21.215 g o-xylene (0.2 mol), 120 mL 1,2 dichloro ethane, and 4.245 g of catalyst as prepared in example 5. The flask was flushed with nitrogen. The reaction mixture was refluxed at 110° C. for 1 h followed by the dropwise addition of 35.6 mL (0.266 mol) 30% HNO3. The water formed during the reaction was removed using reverse dean-stark apparatus. The reaction was carried out for 8 h. The reaction was monitored by GC analysis. In this reaction 28.2% conversion of o-xylene was obtained with 47.3% and 47.3% 3-nitro o-xylene (3NOx) and 4-nitro o-xylene (4NOx), respectively. Other unidentified products were 5.4%.

Provenance & Evidence