HCID 23581881, compound → HCID 12969030, compound

HRID 1479777Notes

Reaction equation

HRID 1479777 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([C:20]2[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=2)C(=O)C2C=CC(CCC)=CC=2)=[CH:4][CH:3]=1.F[C:28]1[CH:29]=[C:30]([CH:48]=[CH:49][C:50]=1O)[C:31](N(C1C=CC(F)=CC=1)C1C=CC(O)=CC=1)=O.O[C:53]1C=CC(N(C2C=CC(O)=CC=2)C(=O)C2C=CC=C(C)C=2C)=CC=1.FC1C=C(C=CC=1O)C(N(C1C=CC(O)=CC=1)C1C=CC(O)=CC=1)=O.FC1C=C(C=CC=1O)C(N(C1C=CC(O)=CC=1)C1C=CC=CC=1)=O.FC1C(C)=C(C=CC=1)C(N(C1C=CC(O)=CC=1)C1C=CC(O)=CC=1)=O>>[CH2:31]([O:26][C:23]1[CH:22]=[CH:21][C:20]([NH:8][C:5]2[CH:4]=[CH:3][C:2]([O:1][CH3:53])=[CH:7][CH:6]=2)=[CH:25][CH:24]=1)[C:30]1[CH:48]=[CH:49][CH:50]=[CH:28][CH:29]=1

Participants

7

Reactant 6

HCID 23581881HCID 23581881, compoundHCID 23581884HCID 23581884, compoundHCID 23582528HCID 23582528, compoundHCID 468615783-Fluoro-N-(4-fluorophenyl)-4-hydroxy-N-(4-hydroxyphenyl)benzamideHCID 46873518HCID 46873518, compoundHCID 46873520HCID 46873520, compound

Product 1

HCID 12969030HCID 12969030, compound

Procedure

The following compounds where synthesized as described herein above and characterized and summarized in Table 1: N,N-bis(4-hydroxyphenyl)-4-propylbenzamide (II); 3-fluoro-N-(4-fluorophenyl)-4-hydroxy-N-(4-hydroxyphenyl)benzamide (IV); N,N-bis(4-hydroxyphenyl)-2,3-dimethylbenzamide (V); 3-fluoro-4-hydroxy-N,N-bis(4-hydroxyphenyl)-benzamide (VII); 3-fluoro-4-hydroxy-N-(4-hydroxyphenyl)-N-phenylbenzamide (XI); and 3-fluoro-N,N-bis(4-hydroxyphenyl)-2-methylbenzamide (XII).

Workup

  1. customThe following compounds where synthesized

Sources & evidence

ORD record
ord-805d7b7cf4dc43d5b7ffcbcc1cb98509
Source dataset
uspto-grants-2016_08
Patent number
US09409856B2

Reaction notes

Loading…