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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 147979Generated: October 30, 2026

Acetyl chloride → Racemic (2'S,3S,4'R)-4'-[2-(1-acetyl-4-piperidinyloxy)-5-bromo-phenyl]-6-chloro-2'-(3-chlorophenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

https://huagongshe.com/reaction/147979

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantRacemic (2'S,3S,4'R)-4'-[5-bromo-2-(4-piperidinyloxy)-phenyl]-6-chloro-2'-(5-chlorophenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dioneHCID 74928458—
ProductRacemic (2'S,3S,4'R)-4'-[2-(1-acetyl-4-piperidinyloxy)-5-bromo-phenyl]-6-chloro-2'-(3-chlorophenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dioneHCID 77285149—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-b812ecc50a6a4cb0b9c8bdaca08b08a0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)