Acetic Anhydride → HCID 60194810, compound

HRID 1479794Notes

Reaction equation

HRID 1479794 reaction equation
CN(C)/[N:3]=[CH:4]/[C:5]([CH3:7])=[CH2:6].C(OC(=O)C)(=O)C.Br[C:17]1[C:18](=[O:25])[CH:19]=[C:20]([CH3:24])[C:21](=[O:23])[CH:22]=1>CC#N>[CH3:7][C:5]1[CH:4]=[N:3][C:22]2[C:21](=[O:23])[C:20]([CH3:24])=[CH:19][C:18](=[O:25])[C:17]=2[CH:6]=1

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 27296292-Bromo-5-methyl-1,4-benzoquinoneHCID 11815318HCID 11815318, compound

Product 1

HCID 60194810HCID 60194810, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent2×

Procedure

(E)-1,1-dimethyl-2-(2-methylallylidene)hydrazine (2.18 g, 19.50 mmol, 1.3 equiv.) and acetic anhydride (19.15 mL) were added in 250 mL of MeCN and stirred at room temperature. 2-bromo-5-methylcyclohexa-2,5-diene-1,4-dione (3 g, 14.9 mmol, 1 equiv.) in 125 mL of MeCN was then added dropwise (slowly during 60 min). The reaction mixture was stirred at room temperature during 120 minutes.

Workup

  1. stirringThe reaction mixture was stirred at room temperature during 120 minutes

Sources & evidence

ORD record
ord-65d37999426b4dd185abc7b3d1b90161
Source dataset
uspto-grants-2016_08
Patent number
US09409879B2

Reaction notes

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