HCID 70810818, compound → HCID 68372440, compound

HRID 1479796Notes

Reaction equation

HRID 1479796 reaction equation
C[O:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([O:13][CH3:14])=[C:5]([CH3:15])[C:4]=1[C:16]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[F:24])=[O:17]>C1CCCCC1.C(Cl)Cl>[F:24][C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[C:16]([C:4]1[C:5]([CH3:15])=[C:6]([O:13][CH3:14])[C:7]2[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]=1[OH:2])=[O:17]

Participants

3

Reactant 1

HCID 70810818HCID 70810818, compound

Product 1

HCID 68372440HCID 68372440, compound

Reagents, catalysts & solvents 1

HCID 21916607Dichloromethane cyclohexaneSolvent

Procedure

(1,4-dimethoxy-3-methylnaphthalen-2-yl)(2-fluorophenyl)methanone LJ103 (75 mg, 0.231 mmol) was treated according to general procedure 12.1. The product was obtained as a yellow powder. Rf(Cyclohexane:DCM 3:2)=0.29. Yield=68 mg (94%).

Workup

  1. customThe product was obtained as a yellow powder

Sources & evidence

ORD record
ord-3bccdd20507149e597aadd1c10a4af05
Source dataset
uspto-grants-2016_08
Patent number
US09409879B2

Reaction notes

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