化工社化工社 化学情報印刷レポート · 研究参考用
(2R)-2-aminopentan-1-ol → 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((R)-1-hydroxymethyl-butyl)-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (2R)-2-aminopentan-1-ol | HCID 5324727 | — |
| 反応物 | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 90203638 | — |
| 生成物 | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid ((R)-1-hydroxymethyl-butyl)-amide | HCID 76282482 | — |
反応手順
The title compound was synthesized in analogy to Example 12d, using 5-chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid and (2R)-2-amino-1-pentanol (CAN 80696-30-6) as starting materials and isolated (72 mg, 77%) as colorless oil; LC-MS (UV peak area, m/z) 100%, 313.1311 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09409866B2 |
| 出典データセット | uspto-grants-2016_08 |
| ORD ID | ord-325944a6410548b58c27b1cec11fdab0 |
| 出典メモ | uspto-grants-2016_08 |