[1-(Aminomethyl)cyclopentyl]methanol → HCID 76282247, compound

HRID 1480065Notes

Reaction equation

HRID 1480065 reaction equation
[Cl:1][C:2]1[C:3]([O:11][CH2:12][CH:13]2[CH2:15][CH2:14]2)=[CH:4][C:5]([C:8]([OH:10])=O)=[N:6][CH:7]=1.[NH2:16][CH2:17][C:18]1([CH2:23][OH:24])[CH2:22][CH2:21][CH2:20][CH2:19]1>>[OH:24][CH2:23][C:18]1([CH2:17][NH:16][C:8]([C:5]2[CH:4]=[C:3]([O:11][CH2:12][CH:13]3[CH2:15][CH2:14]3)[C:2]([Cl:1])=[CH:7][N:6]=2)=[O:10])[CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 22379517[1-(Aminomethyl)cyclopentyl]methanolHCID 902036385-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid

Product 1

HCID 76282247HCID 76282247, compound

Procedure

The title compound was synthesized in analogy to Example 12d, using 5-chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid and 1-(aminomethyl)-cyclopentanemethanol (CAN 2239-31-8) as starting materials and isolated (35 mg, quant.) as colorless oil; LC-MS (UV peak area, m/z) 100%, 339.1470 (MH+).

Workup

  1. customisolated (35 mg, quant.) as colorless oil

Sources & evidence

ORD record
ord-8ff8db64ba624c649943b1ebb92d7eee
Source dataset
uspto-grants-2016_08
Patent number
US09409866B2

Reaction notes

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