HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methylpentan-1-ol → 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-hydroxymethyl-1-methyl-butyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methylpentan-1-ol | HCID 15008405 | — |
| Reactant | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 90203638 | — |
| Product | 5-Chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-hydroxymethyl-1-methyl-butyl)-amide | HCID 76283210 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-chloro-4-cyclopropylmethoxy-pyridine-2-carboxylic acid and 2-amino-2-methyl-1-pentanol (CAN 13893-61-3) as starting materials and isolated (21 mg, 71%) as colorless oil; MS (ESI, m/z): 327.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-8513d1f7bae74194ae1b9cbd865a7544 |
| Source note | uspto-grants-2016_08 |