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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1480090생성일: 2026년 10월 25일

3-(1,3-Thiazol-2-yl)oxetan-3-amine hydrochloride → 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (3-thiazol-2-yl-oxetan-3-yl)-amide

https://huagongshe.com/reaction/1480090

반응식

참여 물질

역할이름HCID투입량
반응물3-(1,3-Thiazol-2-yl)oxetan-3-amine hydrochlorideHCID 86674782—
반응물5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 90203809—
생성물5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (3-thiazol-2-yl-oxetan-3-yl)-amideHCID 76282969—

반응 단계

The title compound was synthesized in analogy to Example 24d, using 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42c) and 3-(thiazol-2-yl)oxetan-3-amine hydrochloride (Example 32b) as starting materials and isolated (16 mg, 29%) as colorless oil; MS (ESI, m/z): 372.2 (M+H+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09409866B2
출처 데이터셋uspto-grants-2016_08
ORD IDord-e3512e3c38644d31858506770f2857d6
출처 메모uspto-grants-2016_08