化工社化工社 化学情報印刷レポート · 研究参考用
2,2-Dimethyl-1-thiazol-2-yl-propylamine → 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (2,2-dimethyl-1-thiazol-2-yl-propyl)-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,2-Dimethyl-1-thiazol-2-yl-propylamine | HCID 20795524 | — |
| 反応物 | 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 90203809 | — |
| 生成物 | 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (2,2-dimethyl-1-thiazol-2-yl-propyl)-amide | HCID 76282965 | — |
反応手順
The title compound was synthesized in analogy to Example 24d, using 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42c) and 2,2-Dimethyl-1-thiazol-2-yl-propylamine (CAN 1247122-26-4) as starting materials and isolated (15 mg, 26%) as white solid; MS (ESI, m/z): 386.4 (M+H+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09409866B2 |
| 出典データセット | uspto-grants-2016_08 |
| ORD ID | ord-4094aadb2779495abb55500680294cdb |
| 出典メモ | uspto-grants-2016_08 |