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HRID 1480092作成日：2026年10月25日

1-Cyclopropyl-1-(5-methyl-1,2,4-oxadiazol-3-yl)ethan-1-amine → 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid [1-cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

https://huagongshe.com/reaction/1480092

反応式

関与物質

役割名称HCID仕込み量
反応物1-Cyclopropyl-1-(5-methyl-1,2,4-oxadiazol-3-yl)ethan-1-amineHCID 43559223—
反応物5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 90203809—
生成物5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid [1-cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amideHCID 76282968—

反応手順

The title compound was synthesized in analogy to Example 24d, using 5-Cyclopropyl-4-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 42c) and 1-Cyclopropyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethylamine (CAN 1155536-64-3) as starting materials and isolated (13 mg, 23%) as colorless oil; MS (ESI, m/z): 383.6 (M+H+)

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09409866B2
出典データセットuspto-grants-2016_08
ORD IDord-c213e5fa60d44cf0b6306ced0f696d87
出典メモuspto-grants-2016_08