N-Methyl-tert-butylamine → HCID 90203481, compound

HRID 1480153Notes

Reaction equation

HRID 1480153 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][N:11]=[C:10]([C:14]([OH:16])=O)[CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[CH3:17][NH:18][C:19]([CH3:22])([CH3:21])[CH3:20]>>[C:19]([N:18]([CH3:17])[C:14]([C:10]1[CH:9]=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[CH:13]=[CH:12][N:11]=1)=[O:16])([CH3:22])([CH3:21])[CH3:20]

Participants

3

Reactant 2

HCID 84552N-Methyl-tert-butylamineHCID 53223002HCID 53223002, compound

Product 1

HCID 90203481HCID 90203481, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 4-(3-chlorophenyl)picolinic acid (CAN 1207725-34-5) and N,2-dimethylpropan-2-amine (CAN 14610-37-8) as starting materials and isolated (10 mg, 77%) as colorless oil; MS (ESI, m/z): 303.4 (MH+).

Workup

  1. customisolated (10 mg, 77%) as colorless oil

Sources & evidence

ORD record
ord-702c94f5babb4d2bb73be741319b9899
Source dataset
uspto-grants-2016_08
Patent number
US09409866B2

Reaction notes

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