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HRID1480159

反应详情

EQUATION

反应方程式

HRID 1480159 的结构方程式

REACTANTS

反应物

2
结构：CC(N)(C#N)C1CC1
HCID3791919

2-amino-2-cyclopropylpropanenitrile

C6H10N2

结构：C[C@H](Oc1cc(C(=O)O)ncc1Br)C(F)(F)F
HCID90203550

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](Oc1cc(C(=O)NC(C)(C#N)C2CC2)ncc1Br)C(F)(F)F
HCID118554275

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 78e, using 5-Bromo-4-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-pyridine-2-carboxylic acid (Example 96d) and 2-amino-2-cyclopropylpropanenitrile (CAN 37024-73-0) as starting materials and isolated (607 mg, 65%) as a yellow oil; MS (ESI, m/z): 420.4 (M+H+).

WORKUP

后处理

  1. customisolated (607 mg, 65%) as a yellow oil