Cyclobutanone → HCID 90203774, compound

HRID 1480192Notes

Reaction equation

HRID 1480192 reaction equation
Br[C:2]1[C:3]([Cl:9])=[CH:4][C:5]([Cl:8])=[N:6][CH:7]=1.[C:10]1(=[O:14])[CH2:13][CH2:12][CH2:11]1>>[Cl:9][C:3]1[CH:4]=[C:5]([Cl:8])[N:6]=[CH:7][C:2]=1[C:10]1([OH:14])[CH2:13][CH2:12][CH2:11]1

Participants

3

Reactant 2

HCID 14496CyclobutanoneHCID 121751335-bromo-2,4-dichloropyridine

Product 1

HCID 90203774HCID 90203774, compound

Procedure

The title compound was synthesized in analogy to Example 123a, using 5-bromo-2,4-dichloropyridine (CAN 849937-96-8) and cyclobutanone (CAN 1191-95-3) as starting materials and isolated (5.1 g, 76%); MS (ESI, m/z): 218.4 (M+H+).

Workup

  1. customisolated (5.1 g, 76%)

Sources & evidence

ORD record
ord-de8d8d33620a439096a33881ce204152
Source dataset
uspto-grants-2016_08
Patent number
US09409866B2

Reaction notes

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