HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → HCID 90204569, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 2-(5-Methyl-1,2,4-oxadiazol-3-yl)-1-methylsulfonyl-propan-2-amine | HCID 90203430 | — |
| Reactant | HCID 90203968 | HCID 90203968 | — |
| Product | HCID 90204569 | HCID 90204569 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 112e, using 5-(3-fluorooxetan-3-yl)-4-(2,2,2-trifluoroethoxy)pyridine-2-carboxylic acid (Example 131b) and 2-(5-methyl-1,2,4-oxadiazol-3-yl)-1-methylsulfonyl-propan-2-amine;hydrobromide (enantiomer B) (example 125b) as starting materials and isolated (35 mg, 42%); MS (ESI, m/z): 497.6 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-ab8493344c5d4fbe8dbae691a98d597b |
| Source note | uspto-grants-2016_08 |