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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480212Generated: November 2, 2026

(2S)-1,1,1-Trifluoropropan-2-ol → HCID 90214967, compound

https://huagongshe.com/reaction/1480212

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-1,1,1-Trifluoropropan-2-olHCID 6999971—
ReactantHCID 90203658HCID 90203658—
ProductHCID 90214967HCID 90214967—

Reaction Steps

The title compound was synthesized in analogy to Example 123c, using 4-chloro-5-(3-fluorooxetan-3-yl)pyridine-2-carbonitrile (Example 131a) and (S)-1,1,1-Trifluoro-propan-2-ol (CAN 3539-97-7) as starting materials and isolated (1.66 g, 61%); MS (ESI, m/z): 291.4 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409866B2
Source datasetuspto-grants-2016_08
ORD IDord-be1fc671741a44e3ad405c9406eaeb82
Source noteuspto-grants-2016_08