HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalic acid--2-oxa-6-azaspiro(3.3)heptane (1/1) → HCID 90203756, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalic acid--2-oxa-6-azaspiro(3.3)heptane (1/1) | HCID 53308464 | — |
| Reactant | HCID 90203702 | HCID 90203702 | — |
| Product | HCID 90203756 | HCID 90203756 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 112e, using 2-[[5-cyclopropyl-4-(2,2,2-trifluoroethoxy)pyridine-2-carbonyl]amino]-2-(5-methyl-1,2,4-oxadiazol-3-yl)propanoic acid (Example 147c) and 2-oxa-6-azaspiro[3.3]heptane oxalate (2:1) (CAN 1045709-32-7) as starting materials and isolated (8 mg, 10%); MS (ESI, m/z): 496.5 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409866B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-afa2a40beaf9414885d312c7d30898ed |
| Source note | uspto-grants-2016_08 |