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HRID1480241

反应详情

EQUATION

反应方程式

HRID 1480241 的结构方程式

REACTANTS

反应物

2
结构：CNC(=O)[C@@H](N)C(C)(C)C
HCID445856

(S)-2-Amino-N-methyl-3,3-dimethylbutanamide

C7H16N2O

结构：C[C@H](Oc1cc(C(=O)O)ncc1C1(F)COC1)C(F)(F)F
HCID90214950

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)[C@@H](NC(=O)c1cc(O[C@@H](C)C(F)(F)F)c(C2(F)COC2)cn1)C(C)(C)C
HCID118539962

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 112e, using 5-(3-fluorooxetan-3-yl)-4-[(1S)-2,2,2-trifluoro-1-methyl-ethoxy]pyridine-2-carboxylic acid (example 142b) and (S)-2-Amino-3,3,N-trimethyl-butyramide (CAN 89226-12-0) as starting materials and isolated (40 mg, 57%); MS (ESI, m/z): 436.6 (M+H+).

WORKUP

后处理

  1. customisolated (40 mg, 57%)