huagongshe.com
HRID1480269

反应详情

EQUATION

反应方程式

HRID 1480269 的结构方程式

REACTANTS

反应物

3
结构：C1CNC1
HCID10422

Azetidine

C3H7N

结构：O=C([O-])[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.O=C([O-])[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[Mg+2]
HCID11418570

Magnesium gluconate anhydrous

C12H22MgO14

结构：CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C(=O)O
HCID90203975

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C(=O)N1CCC1
HCID76281460

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 112e, using 2-[[5-cyclopropyl-4-(2,2,2-trifluoroethoxy)pyridine-2-carbonyl]amino]-3,3-dimethyl-butanoic acid (Example 194b) and azetidine (CAN 503-29-7) as starting materials and isolated (29 mg, 54%); MS (ESI, m/z): 414.6 (M+H+).

WORKUP

后处理

  1. customisolated (29 mg, 54%)