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HRID1480280

反应详情

EQUATION

反应方程式

HRID 1480280 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)C(N)C#N
HCID11378465

2-amino-3,3-dimethylbutanenitrile

C6H12N2

结构：C[C@H](Oc1cc(C(=O)O)ncc1C1CC1)C(F)(F)F
HCID90204573

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](Oc1cc(C(=O)NC(C#N)C(C)(C)C)ncc1C1CC1)C(F)(F)F
HCID90214975

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 112e, using 5-Cyclopropyl-4-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-pyridine-2-carboxylic acid (Example 68a) and 2-Amino-3,3-dimethyl-butyronitrile (CAN 77425-86-6) as starting materials and isolated (2 g, 99%); MS (ESI, m/z): 370.6 (M+H+).

WORKUP

后处理

  1. customisolated (2 g, 99%)