Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(3,3-Difluoroazetidin-1-yl)-4-(2,2,2-trifluoroethoxy)picolinic acid → HCID 90204495, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(3,3-Difluoroazetidin-1-yl)-4-(2,2,2-trifluoroethoxy)picolinic acid | HCID 90204045 | — |
| 반응물 | 2-(3-Amino-1,1-dioxo-thietan-3-yl)acetamide | HCID 90213830 | — |
| 생성물 | HCID 90204495 | HCID 90204495 | — |
반응 단계
The title compound was synthesized in analogy to Example 112e, using 5-(3,3-difluoroazetidin-1-yl)-4-(2,2,2-trifluoroethoxy)pyridine-2-carboxylic acid (example 223b) and 2-(3-amino-1,1-dioxo-thietan-3-yl)acetamide (example 160d) as starting materials and isolated (20 mg, 27%); MS (ESI, m/z): 473.3 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09409866B2 |
| 출처 데이터셋 | uspto-grants-2016_08 |
| ORD ID | ord-063ab41f3178427f87927818ba5f0e5d |
| 출처 메모 | uspto-grants-2016_08 |