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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480367Generated: November 2, 2026

Diethyl squarate → 3,5-Dichlorobenzyl 4-(2-((2-ethoxy-3,4-dioxocyclobut-1-en-1-yl)amino)ethyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/1480367

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl squarateHCID 123228—
Reactant3,5-Dichlorobenzyl 4-(2-aminoethyl)piperidine-1-carboxylateHCID 86722626—
Product3,5-Dichlorobenzyl 4-(2-((2-ethoxy-3,4-dioxocyclobut-1-en-1-yl)amino)ethyl)piperidine-1-carboxylateHCID 76284149—

Reaction Steps

The title compound was prepared from 3,4-diethoxycyclobut-3-ene-1,2-dione and 3,5-dichlorobenzyl 4-(2-aminoethyl)piperidine-1-carboxylate (step 1) analogously to Example 2;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409895B2
Source datasetuspto-grants-2016_08
ORD IDord-a4bf4e555fed40b3b25d51f27f8c20cd
Source noteuspto-grants-2016_08