HCID 86722625, compound → HCID 178483288, compound

HRID 1480412Notes

Reaction equation

HRID 1480412 reaction equation
[OH:1][C:2]1[NH:6][N:5]=[C:4]([C:7]([OH:9])=O)[CH:3]=1.[CH3:10][NH:11][CH2:12][CH2:13][CH:14]1[CH2:19][CH2:18][N:17]([C:20]([O:22][CH2:23][C:24]2[CH:29]=[C:28]([Cl:30])[CH:27]=[C:26]([Cl:31])[CH:25]=2)=[O:21])[CH2:16][CH2:15]1>>[OH:1][C:2]1[NH:6][N:5]=[C:4]([C:7]([N:11]([CH2:12][CH2:13][CH:14]2[CH2:15][CH2:16][N:17]([C:20]([O:22][CH2:23][C:24]3[CH:25]=[C:26]([Cl:31])[CH:27]=[C:28]([Cl:30])[CH:29]=3)=[O:21])[CH2:18][CH2:19]2)[CH3:10])=[O:9])[CH:3]=1

Participants

3

Reactant 2

HCID 86722625HCID 86722625, compoundHCID 178524640HCID 178524640, compound

Product 1

HCID 178483288HCID 178483288, compound

Procedure

The title compound was prepared from commercially available 5-hydroxy-1H-pyrazole-3-carboxylic acid and 3,5-dichlorobenzyl 4-(2-(methylamino)ethyl)piperidine-1-carboxylate (Example 1, step 3) analogously to Example 15 step 3;

Sources & evidence

ORD record
ord-93170bbf914d4b05925988869bf73975
Source dataset
uspto-grants-2016_08
Patent number
US09409895B2

Reaction notes

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