HCID 86722625, compound → HCID 136216096, compound

HRID 1480418Notes

Reaction equation

HRID 1480418 reaction equation
[O:1]=[C:2]1[O:6][N:5]=[C:4]([C:7]([OH:9])=O)[NH:3]1.[CH3:10][NH:11][CH2:12][CH2:13][CH:14]1[CH2:19][CH2:18][N:17]([C:20]([O:22][CH2:23][C:24]2[CH:29]=[C:28]([Cl:30])[CH:27]=[C:26]([Cl:31])[CH:25]=2)=[O:21])[CH2:16][CH2:15]1>>[CH3:10][N:11]([CH2:12][CH2:13][CH:14]1[CH2:15][CH2:16][N:17]([C:20]([O:22][CH2:23][C:24]2[CH:25]=[C:26]([Cl:31])[CH:27]=[C:28]([Cl:30])[CH:29]=2)=[O:21])[CH2:18][CH2:19]1)[C:7]([C:4]1[NH:3][C:2](=[O:1])[O:6][N:5]=1)=[O:9]

Participants

3

Reactant 2

HCID 86722625HCID 86722625, compoundHCID 135973146HCID 135973146, compound

Product 1

HCID 136216096HCID 136216096, compound

Procedure

The title compound was prepared from commercially available 5-oxo-4,5-dihydro-1,2,4-oxadiazole-3-carboxylic acid and 3,5-dichlorobenzyl 4-(2-(methylamino)ethyl)piperidine-1-carboxylate (Example 1, step 3) analogously to Example 15 step 3;

Sources & evidence

ORD record
ord-b6b96feba6f54c3d8e479e661c5053ab
Source dataset
uspto-grants-2016_08
Patent number
US09409895B2

Reaction notes

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