4-Carboxy-1,2,3-triazole → HCID 178483290, compound

HRID 1480433Notes

Reaction equation

HRID 1480433 reaction equation
[NH:1]1[CH:5]=[C:4]([C:6]([OH:8])=O)[N:3]=[N:2]1.[CH3:9][NH:10][CH2:11][CH2:12][CH:13]1[CH2:18][CH2:17][N:16]([C:19]([O:21][CH2:22][C:23]2[CH:28]=[C:27]([Cl:29])[CH:26]=[C:25]([Cl:30])[CH:24]=2)=[O:20])[CH2:15][CH2:14]1>>[CH3:9][N:10]([CH2:11][CH2:12][CH:13]1[CH2:14][CH2:15][N:16]([C:19]([O:21][CH2:22][C:23]2[CH:24]=[C:25]([Cl:30])[CH:26]=[C:27]([Cl:29])[CH:28]=2)=[O:20])[CH2:17][CH2:18]1)[C:6]([C:4]1[N:3]=[N:2][NH:1][CH:5]=1)=[O:8]

Participants

3

Reactant 2

HCID 1401204-Carboxy-1,2,3-triazoleHCID 86722625HCID 86722625, compound

Product 1

HCID 178483290HCID 178483290, compound

Procedure

The title compound was prepared analogously to Example 34, step 3 from 1H-1,2,3-triazole-4-carboxylic acid and 3,5-dichlorobenzyl 4-(2-(methylamino)ethyl)piperidine-1-carboxylate (Example 1, step 3) (200 mg, 0.579 mmol);

Sources & evidence

ORD record
ord-a4e683597f154ca5b2925ad48f5eee83
Source dataset
uspto-grants-2016_08
Patent number
US09409895B2

Reaction notes

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