Hydrochloric Acid → 3,5-Dichlorobenzyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride

Participants

Reaction Steps

A reaction mixture comprising of 3,5-dichlorobenzyl 4-(((tert-butoxycarbonyl)amino)methyl)piperidine-1-carboxylate (947 mg, 2.269 mmol) and 4M HCl in dioxane (2.84 mL, 11.35 mmol) in DCM (5 mL) was stirred at room temperature for 3 hours. The reaction mixture was concentrated under reduced pressure to give the title compound as the hydrochloride salt;

Provenance & Evidence