3,5-Dichlorobenzyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride → HCID 178520524, compound

HRID 1480469Notes

Reaction equation

HRID 1480469 reaction equation
Cl.[NH2:2][CH2:3][CH:4]1[CH2:9][CH2:8][N:7]([C:10]([O:12][CH2:13][C:14]2[CH:19]=[C:18]([Cl:20])[CH:17]=[C:16]([Cl:21])[CH:15]=2)=[O:11])[CH2:6][CH2:5]1.[NH:22]1[CH:26]=[C:25]([CH2:27][CH2:28][C:29](O)=[O:30])[N:24]=[N:23]1>>[NH:24]1[C:25]([CH2:27][CH2:28][C:29]([NH:2][CH2:3][CH:4]2[CH2:9][CH2:8][N:7]([C:10]([O:12][CH2:13][C:14]3[CH:15]=[C:16]([Cl:21])[CH:17]=[C:18]([Cl:20])[CH:19]=3)=[O:11])[CH2:6][CH2:5]2)=[O:30])=[CH:26][N:22]=[N:23]1

Participants

3

Reactant 2

HCID 867226743,5-Dichlorobenzyl 4-(aminomethyl)piperidine-1-carboxylate hydrochlorideHCID 178525362HCID 178525362, compound

Product 1

HCID 178520524HCID 178520524, compound

Procedure

The title compound was prepared from 3,5-dichlorobenzyl 4-(aminomethyl)piperidine-1-carboxylate hydrochloride (Example 41, step 2) and 3-(1H-1,2,3-triazol-4-yl)propanoic acid (step 1) analogously to Example 41 step 3;

Sources & evidence

ORD record
ord-74d4b7cf97c04536b56cccde38735eb7
Source dataset
uspto-grants-2016_08
Patent number
US09409895B2

Reaction notes

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