Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480493Generated: November 3, 2026

Hydrochloric Acid → HCID 86722708, compound

https://huagongshe.com/reaction/1480493

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 86722706HCID 86722706—
SolventDichloromethaneHCID 6344—
ProductHCID 86722708HCID 86722708—

Reaction Steps

3-Cyano-5-(trifluoromethyl)benzyl 4-((tert-butoxycarbonyl)amino)piperidine-1-carboxylate (119 mg, 0.278 mmol) was dissolved in DCM (5 ml) and 4M HCl in Dioxane (0.696 ml, 2.78 mmol) was added with stirring at RT under nitrogen. After 3 hrs, the mixture was concentrated in vacuo to give the title compound as the hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409895B2
Source datasetuspto-grants-2016_08
ORD IDord-3d6b659fe9c748ef88bcb7607b66f9ac
Source noteuspto-grants-2016_08