4-(3-Boronophenyl)butanoic acid → HCID 178422042, compound

HRID 1480523Notes

Reaction equation

HRID 1480523 reaction equation
C(C1C=C([C:10]2=[C:11]([CH:37]=[CH:38][C:39]3[C:47]([CH3:49])([CH3:48])[C:46]4[C:41](=[CH:42][CH:43]=[C:44]([S:50]([O-:53])(=[O:52])=[O:51])[CH:45]=4)[N+:40]=3[CH2:54][CH2:55][CH2:56][CH2:57][S:58]([O-:61])(=[O:60])=[O:59])[CH2:12][CH2:13]/[C:14]/2=[CH:15]\[CH:16]=[C:17]2/[C:18]([CH3:36])([CH3:35])[C:19]3[C:20](=[N:34]/2)[N:21]([CH2:26][CH2:27][CH2:28][CH2:29][S:30]([O-:33])(=[O:32])=[O:31])[CH:22]=[C:23]([Cl:25])[CH:24]=3)C=CC=1)(O)=O.[Na+:62].[Na+].B([C:67]1[CH:68]=[C:69]([CH2:73][CH2:74][CH2:75][C:76]([OH:78])=[O:77])[CH:70]=[CH:71][CH:72]=1)(O)O>>[C:76]([CH2:75][CH2:74][CH2:73][C:69]1[CH:68]=[C:67]([C:10]2=[C:11]([CH:37]=[CH:38][C:39]3[C:47]([CH3:49])([CH3:48])[C:46]4[C:41](=[CH:42][CH:43]=[C:44]([S:50]([O-:53])(=[O:52])=[O:51])[CH:45]=4)[N+:40]=3[CH2:54][CH2:55][CH2:56][CH2:57][S:58]([O-:61])(=[O:60])=[O:59])[CH2:12][CH2:13]/[C:14]/2=[CH:15]\[CH:16]=[C:17]2/[C:18]([CH3:35])([CH3:36])[C:19]3[C:20](=[N:34]/2)[N:21]([CH2:26][CH2:27][CH2:28][CH2:29][S:30]([O-:33])(=[O:32])=[O:31])[CH:22]=[C:23]([Cl:25])[CH:24]=3)[CH:72]=[CH:71][CH:70]=1)([OH:78])=[O:77].[Na+:62].[Na+:62]

Participants

3

Reactant 2

HCID 596235194-(3-Boronophenyl)butanoic acidHCID 178422043HCID 178422043, compound

Product 1

HCID 178422042HCID 178422042, compound

Procedure

Compound 41 is prepared analogously to compound 40 (Example 51), except with 4-(3-boronophenyl)butanoic acid as a starting material.

Sources & evidence

ORD record
ord-487542b3b01346139bb9e5264e5d96de
Source dataset
uspto-grants-2016_08
Patent number
US09408924B2

Reaction notes

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