Acetaldehyde → HCID 86603271, compound

HRID 14806Notes

Reaction equation

HRID 14806 reaction equation
[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:25]=[CH:26][CH:27]=2)[CH2:11][NH:12][CH2:13][CH2:14][CH2:15][NH:16][C:17](=[O:24])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:5]=[CH:4][N:3]=1.[CH:28](=O)[CH3:29]>>[Cl:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:25]=[CH:26][CH:27]=2)[CH2:11][N:12]([CH2:28][CH3:29])[CH2:13][CH2:14][CH2:15][NH:16][C:17](=[O:24])[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 177AcetaldehydeHCID 86603272N-{3-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-propyl}-benzamide

Product 1

HCID 86603271HCID 86603271, compound

Procedure

Intermediate 43 was coupled with acetaldehyde following procedure E. LC-MS showed the product had the expected M+H+ of 409.

Sources & evidence

ORD record
ord-bf4fa77d52914816af41ad9724bc32cc
Source dataset
uspto-grants-2010_06
Patent number
US07732444B2

Reaction notes

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