Tyramine → HCID 58603605, compound

HRID 14807Notes

Reaction equation

Cl[C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10]([CH:27]=[CH:28][CH:29]=2)[CH2:11][N:12]([CH2:25][CH3:26])[CH2:13][CH2:14][CH2:15][NH:16][C:17](=[O:24])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:5]=[CH:4][N:3]=1.[NH2:30][CH2:31][CH2:32][C:33]1[CH:38]=[CH:37][C:36]([OH:39])=[CH:35][CH:34]=1>>[CH2:25]([N:12]([CH2:11][C:10]1[CH:27]=[CH:28][CH:29]=[C:8]([C:6]2[CH:5]=[CH:4][N:3]=[C:2]([NH:30][CH2:31][CH2:32][C:33]3[CH:38]=[CH:37][C:36]([OH:39])=[CH:35][CH:34]=3)[N:7]=2)[CH:9]=1)[CH2:13][CH2:14][CH2:15][NH:16][C:17](=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH3:26]

Participants

Reactant 2

HCID 5610Tyramine

HCID 86603271HCID 86603271, compound

Product 1

HCID 58603605HCID 58603605, compound

Procedure

Intermediate 44 was coupled with tyramine following procedure F. LC-MS showed the product had the expected M+H+ of 510.

Sources & evidence

ORD record: ord-237ccfcafb5641cc83b62a290e2ebb9c
Source dataset: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07732444B2

Reaction notes

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