HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-1,2,4-Triazole, 5-bromo-1-methyl- → 2-methoxy-4-(1-methyl-1H-1,2,4-triazol-5-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-1,2,4-Triazole, 5-bromo-1-methyl- | HCID 140121 | — |
| Reactant | 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline | HCID 17750207 | — |
| Product | 2-methoxy-4-(1-methyl-1H-1,2,4-triazol-5-yl)aniline | HCID 89995634 | — |
Reaction Steps
The title compound was prepared according to the method described for Preparation 158 using 5-bromo-1-methyl-1H-1,2,4-triazole and 2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline. The residue was purified using Biotage silica gel column chromatography eluting with EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409907B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-16ad50d2510c4303bcd7423a063f6ef6 |
| Source note | uspto-grants-2016_08 |