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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1480850Generated: November 3, 2026

1H-1,2,4-Triazole, 5-bromo-1-methyl- → 2-methoxy-4-(1-methyl-1H-1,2,4-triazol-5-yl)aniline

https://huagongshe.com/reaction/1480850

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-1,2,4-Triazole, 5-bromo-1-methyl-HCID 140121—
Reactant2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anilineHCID 17750207—
Product2-methoxy-4-(1-methyl-1H-1,2,4-triazol-5-yl)anilineHCID 89995634—

Reaction Steps

The title compound was prepared according to the method described for Preparation 158 using 5-bromo-1-methyl-1H-1,2,4-triazole and 2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline. The residue was purified using Biotage silica gel column chromatography eluting with EtOAc.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409907B2
Source datasetuspto-grants-2016_08
ORD IDord-16ad50d2510c4303bcd7423a063f6ef6
Source noteuspto-grants-2016_08