HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → (2S)-4-amino-2-(((tert-butoxy)carbonyl)amino)butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Boc-L-2,4-diaminobutyric acid(Fmoc) | HCID 2755945 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | (2S)-4-amino-2-(((tert-butoxy)carbonyl)amino)butanoic acid | HCID 7019666 | — |
Reaction Steps
Boc-L-Dab(Fmoc)-OH (132 mg, 0.3 mmol, PepTech) and piperidine (0.2 mL, 2.02 mmol) were dissolved in DMF (1 mL). The resulting mixture was stirred at room temperature for 30 minutes. The volatiles were removed in vacuo and the residue was used directly in the subsequent step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409892B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-e6a05d0cb9c749679e54cfa24643962d |
| Source note | uspto-grants-2016_08 |