HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → Boc-D-2,4-diaminobutyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | (2R)-2-{[(tert-butoxy)carbonyl]amino}-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid | HCID 17040123 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Boc-D-2,4-diaminobutyric acid | HCID 7021116 | — |
Reaction Steps
Boc-D-Dab(Fmoc)-OH (206 mg, 0.5 mmol, Oakwood Products) and piperidine (0.3 mL, 3.03 mmol) were dissolved in DMF (1.6 mL). The resulting mixture was stirred at room temperature for 30 minutes. The volatiles were removed in vacuo and the residue was used directly in the subsequent step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409892B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-65e57136971f48aa98e198a154513e6a |
| Source note | uspto-grants-2016_08 |