HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylurea → 7-(3-Benzyl-ureido)-4-hydroxy-isoquinoline-3-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylurea | HCID 10853 | — |
| Reactant | Ethyl 7-bromo-4-hydroxyisoquinoline-3-carboxylate | HCID 89813095 | — |
| Product | 7-(3-Benzyl-ureido)-4-hydroxy-isoquinoline-3-carboxylic acid ethyl ester | HCID 89812935 | — |
Reaction Steps
7-(3-Benzyl-ureido)-4-hydroxy-isoquinoline-3-carboxylic acid ethyl ester was prepared from 7-bromo-4-hydroxy-isoquinoline-3-carboxylic acid ethyl ester under conditions analogous to Example 116(a) using benzyl urea. The crude product was used in the following steps without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409892B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-903b8f274c344b76a30020c6768cd8a8 |
| Source note | uspto-grants-2016_08 |