Phosgeniminium chloride → HCID 71281789, compound

Participants

Reaction Steps

To a solution of methyl 4-amino-3-hydroxybenzoate (1.63 g, 9.8 mmol) in CH2Cl2 (30 mL) was added N-(dichloromethylene)-N-methylmethanaminium chloride (1.63 g, 10.0 mmol, 1.0 eq). The mixture was heated to reflux for 3 h. The reaction was quenched with H2O then extracted with CH2Cl2 (3×30 mL). Solvent was removed under reduced pressure to afford the title compound (2.2 g, ca. 10.0 mmol) which was used in next step without further purification.

Provenance & Evidence