HCID 71284382, compound → HCID 71284929, compound

Participants

Reaction Steps

To a solution of methyl 1-(2,4-dimethoxybenzyl)-5-ethyl-6-(1-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-7-yl)-2-oxo-1,2-dihydropyridine-3-carboxylate (1.3 g, 2.6 mmol) in CH2Cl2 (20 mL) was added MnO2 in two batches over 2 hrs (2.3 g, 26 mmol). The reaction mixture was then filtered through celite and concentrated to afford the title compound as an orange solid (1.1 g, 85%).

Provenance & Evidence