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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1481746Generated: November 1, 2026

HCID 71285152, compound → HCID 71284811, compound

https://huagongshe.com/reaction/1481746

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 71285152HCID 71285152—
CatalystManganese dioxideHCID 14801—
SolventDichloromethaneHCID 6344—
ProductHCID 71284811HCID 7128481172%

Reaction Steps

To a solution of methyl 5-ethyl-4-hydroxy-6-(1-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-7-yl)-2-oxo-1,2-dihydropyridine-3-carboxylate (1.4 g, 3.8 mmol) in CH2Cl2 (20 mL) was added MnO2 (2.2 g, 25 mmol). After stirring at room temperature for 2 h, the reaction mixture was filtered through celite and concentrated to afford the title compound as a brown solid (1.0 g, 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09409905B2
Source datasetuspto-grants-2016_08
ORD IDord-92199a91f76744b7805dda63c4d7ff9c
Source noteuspto-grants-2016_08