HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 71285152, compound → HCID 71284811, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 71285152 | HCID 71285152 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 71284811 | HCID 71284811 | 72% |
Reaction Steps
To a solution of methyl 5-ethyl-4-hydroxy-6-(1-hydroxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-7-yl)-2-oxo-1,2-dihydropyridine-3-carboxylate (1.4 g, 3.8 mmol) in CH2Cl2 (20 mL) was added MnO2 (2.2 g, 25 mmol). After stirring at room temperature for 2 h, the reaction mixture was filtered through celite and concentrated to afford the title compound as a brown solid (1.0 g, 72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409905B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-92199a91f76744b7805dda63c4d7ff9c |
| Source note | uspto-grants-2016_08 |