Dichloromethane → HCID 71284112, compound

Participants

Reaction Steps

The intermediate from Step 2 (19 mg, 0.030 mmol) was stirred in TFA (0.2 mL), CH2Cl2 (0.2 mL) and TIPSH (0.2 mL) at room temperature for 15 h. The solvents were removed and the residue was dissolved in CH2Cl2 (0.5 mL), then HCl (2.0M in Et2O, 1.0 mL) was added. The precipitate was collected by filtration and washed by ether to afford the title compound as an off-white solid (12 mg, 0.030 mmol, HCl salt) in 100% yield.

Provenance & Evidence