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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 14820Generated: October 26, 2026

2,4-Dichloropyrimidine → 2-Chloro-4-(4-propoxy-phenyl)-pyrimidine

https://huagongshe.com/reaction/14820

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichloropyrimidineHCID 77531—
Reactant4-Propoxyphenylboronic AcidHCID 4456490—
Product2-Chloro-4-(4-propoxy-phenyl)-pyrimidineHCID 79079142—

Reaction Steps

2,4 dichloropyrimidine was coupled with 4-propoxyphenylboronic acid following procedure A. LC-MS showed the product had the expected M+H+ of 249.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732444B2
Source datasetuspto-grants-2010_06
ORD IDord-a146f58063bc4a95bb4d3243df62ae4d
Source noteuspto-grants-2010_06