HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-fluorophenol → (S)-2-Bromo-4-fluoro-1-(pent-4-en-2-yloxy)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-fluorophenol | HCID 605472 | — |
| Reactant | (S)-1-Bromo-4-fluoro-2-(pent-4-en-2-yloxy)benzene | HCID 118308842 | — |
| Product | (S)-2-Bromo-4-fluoro-1-(pent-4-en-2-yloxy)benzene | HCID 118308863 | 88% |
Reaction Steps
Prepared from 2-bromo-4-fluorophenol in 88% yield following the same procedure as (S)-1-bromo-4-fluoro-2-(pent-4-en-2-yloxy)benzene. 1H NMR (400 MHz, CDCl3) δ 7.39-7.33 (m, 1H), 7.30 (dd, J=8.0, 3.0 Hz, 1H), 7.01-6.94 (m, 1H), 6.91-6.85 (m, 1H), 5.90 (ddt, J=17.2, 10.2, 7.0 Hz, 1H), 5.20-5.10 (m, 2H), 4.36 (sxt, J=6.1 Hz, 1H), 2.58-2.49 (m, 1H), 2.45-2.36 (m, 1H), 1.34 (d, J=6.0 Hz, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409922B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-94177c987586494cb3c40f138c3c6e75 |
| Source note | uspto-grants-2016_08 |