HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-3,5-difluorophenol → (S)-2-Bromo-1,5-difluoro-3-(pent-4-en-2-yloxy)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-3,5-difluorophenol | HCID 22144860 | — |
| Reactant | (S)-1-Bromo-4-fluoro-2-(pent-4-en-2-yloxy)benzene | HCID 118308842 | — |
| Product | (S)-2-Bromo-1,5-difluoro-3-(pent-4-en-2-yloxy)benzene | HCID 118308799 | 75% |
Reaction Steps
Prepared in 75% yield from 2-bromo-3,5-difluorophenol following the same procedure as (S)-1-bromo-4-fluoro-2-(pent-4-en-2-yloxy)benzene. 1H NMR (400 MHz, CDCl3) δ 6.59-6.43 (m, 2H), 5.94-5.80 (m, 1H), 5.22-5.09 (m, 2H), 4.47-4.36 (m, 1H), 2.59-2.37 (m, 2H), 1.37 (d, J=6.3 Hz, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409922B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-1ab7901fa83d4fc18d62405853a8e1ec |
| Source note | uspto-grants-2016_08 |