HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-Bromo-5-fluoro-4-methyl-2-(pent-4-en-2-yloxy)benzene → (S)-(5-fluoro-4-methyl-2-(pent-4-en-2-yloxy)phenyl)boronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-Bromo-5-fluoro-4-methyl-2-(pent-4-en-2-yloxy)benzene | HCID 89971081 | — |
| Reactant | (S)-(4-Fluoro-2-(pent-4-en-2-yloxy)phenyl)boronic acid | HCID 123945833 | — |
| Product | (S)-(5-fluoro-4-methyl-2-(pent-4-en-2-yloxy)phenyl)boronic acid | HCID 123357166 | 100% |
Reaction Steps
Prepared in 100% yield from (S)-1-bromo-5-fluoro-4-methyl-2-(pent-4-en-2-yloxy)benzene following the procedure for (S)-(4-fluoro-2-(pent-4-en-2-yloxy)phenyl)boronic acid. NMR is complex and suggests an oligomeric mixture. The material, however, was used as is and was fully compentent for undergoing a Suzuki coupling.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09409922B2 |
| Source dataset | uspto-grants-2016_08 |
| ORD ID | ord-1f2fdf6cc894403a96b026e86423be6a |
| Source note | uspto-grants-2016_08 |