HCID 67330476, compound → HCID 58374619, compound

Participants

Reaction Steps

Cyclopropanecarboxylic acid {5-[4-((E)-2-pyridin-3-yl-vinyl)-phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl}-amide (320 mg, 0.84 mol) was dissolved in 10 mL MeOH. Pd/C (50 mg) was added and the reaction is put under H2 at normal pressure. The reaction was stirred for 2 hrs. The reaction mixture was filtered through Celite®. The organic solvent was removed under pressure. NaHCO3 saturated solution was added to resulting mixture. The compound was extracted with EtOAc. The organic phase was dried over MgSO4, filtered and removed under vacuum to afford the title compound in 100% yield.

Provenance & Evidence