2-Methylbenzoic acid → HCID 73673676, compound

HRID 1482522Notes

Reaction equation

HRID 1482522 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=O.[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([CH:18]([N:21]2[CH2:26][CH2:25][C:24]([F:28])([F:27])[CH2:23][CH2:22]2)[CH2:19][NH2:20])=[CH:14][CH:13]=1>>[Cl:11][C:12]1[CH:13]=[CH:14][C:15]([CH:18]([N:21]2[CH2:22][CH2:23][C:24]([F:28])([F:27])[CH2:25][CH2:26]2)[CH2:19][NH:20][C:4](=[O:6])[C:3]2[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=2[CH3:1])=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 83732-Methylbenzoic acidHCID 86716018HCID 86716018, compound

Product 1

HCID 73673676HCID 73673676, compound

Procedure

From 2-methylbenzoic acid and 2-(4-chloro-phenyl)-2-(4,4-difluoro-piperidin-1-yl)-ethylamine.

Sources & evidence

ORD record
ord-9162adb0ac9f483dab889ade6ba18b52
Source dataset
uspto-grants-2016_08
Patent number
US09415055B2

Reaction notes

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